anti-mouse VEGFR-2/Flk-1 (Peptide), soluble polyclonal antibody Anti-Mouse 100 µg
Description / anti-mouse VEGFR-2/Flk-1 (Peptide), soluble polyclonal antibody
The antibody recognizes solely the endogenous soluble form of mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. The endogenous soluble mouse esFlk-1 generated by alternative splicing consists of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Biological Activity | Western Blot: use at 1-5 µg/ml. |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% |
| Preparation | Produced from sera of rabbits immunised with a peptide of the C-terminal end of native mouse soluble VEGFR-2/Flk-1 (GMEASLGDRIAMP). Anti-human soluble VEGFR-2/KDR was purified by affinity chromatography with immobilized Protein A. |
| Antigen | peptide: GMEASLGDRIAMP |
| Application | WB |
| Synonyms | soluble vascular endothelial growth factor receptor-2 ; soluble Kdr; soluble Ly73; soluble Flk-1; sVEGFR2; sVEGF receptor 2; soluble kinase insert domain protein receptor |
| Uniprot ID | P35918 |
| Protein RefSeq | ACJ66293.1 |
| mRNA RefSeq | EU884114 |