Description / TNFSF13B beta
BAFF (B cell activating factor) is a cytokine of the TNF superfamily and essential for the activation, differentiation and survival of B cells, produced predominantly by neutrophils, monocytes, macrophages and dendritic cells in mammals. Synonyms include TNFSF13B (tumor necrosis factor superfamily member 13B), BLyS (B lymphocyte stimulator), TALL-1, zTNF4[2] or CD257 antigen (cluster of differentiation 257). It is a 285 amino acid long glycoprotein with glycosylation at site 124 and exists as a type 2 transmembrane protein. An isoform exists that lacks the membrane anchor and is therefore freely mobile in the cytosol. It is formed by post-translational modification and contains 152 amino acids.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#2J39) |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Antigen | Mouse recombinant protein TNFSF13B |
| Application | WB |
| Synonyms | TNFSF13B (tumor necrosis factor superfamily member 13B), BLyS (B lymphocyte stimulator), TALL-1, zTNF4[2], CD257-Antigen (Cluster of differentiation 257) |
| Uniprot ID | Q9WU72 |
| Protein RefSeq | NP_296371.1 |
| mRNA RefSeq | NM_033622.1 |