Description / TNF R2
CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF- α and β.
More Information
| Size | 100 µg |
|---|---|
| Source | Armenian Hamster |
| Isotype | IgG |
| Biological Activity | FC: 1:100-1000, IP: 1:100-200 |
| Clone Nr. | (#6F13) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a Armenian Hamster) immunized with mouse recombinant extracellular domain of mouse TNFR-2. IgG fraction of the tissue culture supernatant was purified by Protein G aff |
| Antigen | recombinant mouse EC domain of mouse TNFR-II |
| Application | ELISA, WB, FC, IP |
| Synonyms | Tnfrsf1b; p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2 |
| Uniprot ID | P25119 |
| Protein RefSeq | NP_035740.2 |
| mRNA RefSeq | NM_011610.3 |