anti-mouse TNF-alpha polyclonal antibody Anti-Mouse 100 µg

In stock

Cat-Nr.
103-P35G
Size
100 µg
  €271.00

Description / anti-mouse TNF-alpha polyclonal antibody

TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant murine TNF-α is a soluble 156 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.

More Information

Size 100 µg
Source Goat
Clone Nr. Goat IgG
Species Reactivity Mouse
Formulation lyophilized from PBS
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Preparation Produced from sera of goats pre-immunized with highly pure (>98%) recombinant mTNF-alpha. Anti-mTNF-alpha specific antibody was purified by affinity chromatography employing immobilized mTNF-alpha matrix.
Antigen recombinant mouse TNF-alpha
Application ELISA, WB, N
Synonyms Tnf; DIF; Tnfa; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha
Uniprot ID P06804
Protein RefSeq NP_038721.1
mRNA RefSeq NM_013693.2

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