human TGF-alpha (Animal Free) protein Human 20 µg

In stock

Cat-Nr.
100-103S-AF
Size
20 µg
  €139.00

Description / human TGF-alpha (Animal Free) protein

TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces anchorage-independent transformation in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant Human TGF-α is a 50 amino acid polypeptide (5.5 kDa), which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.

More Information

Size 20 µg
Source E. coli
Biological Activity Determined by its ability to stimulate the proliferation of mouse Balb/c 3T3 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
Purity Confirmation ≥ 98% by SDS-PAGE gel and HPLC analyses.
Length [aa] 50
Molecular Weight 5.5 kDa
Species Reactivity Chicken, Horse, Human, Mouse, Rat
Formulation lyophilized
Protein Sequence VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
Synonyms TGFA; TFGA
Uniprot ID P01135
Protein RefSeq NP_003227.1
mRNA RefSeq NM_003236

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