Description / anti-human RANTES monoclonal antibody
RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2b |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Monoclonal antibody against human RANTES designated as VL-1 was purified from ascites fluid on a Protein A affinity column. The monoclonal antibody was derived form BALB/c mice and belongs to the IgG2b isotype. |
| Antigen | Recombinant Human RANTES (CCL5) |
| Application | ELISA, N, WB, IHC |
| Synonyms | CCL5; SISd; SCYA5; RANTES; TCP228; D17S136E |
| Uniprot ID | P13501 |
| Protein RefSeq | NP_002976.2 |
| mRNA RefSeq | NM_002985 |