Human MEC (CCL28)
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| Cat-Nr. | 100-246 |
| Size | 20 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 108 |
| Molecular Weight | 12.3 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml. |
| Species Reactivity | Human, Bacteria |
| Synonyms | CCL28; MEC; CCK1; SCYA28 |
| Description | MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary glad, mammary gland and colon. MEC signals through the CCR10 receptor and chemoattracts resting CD4, CD8 T-cells and eosinophils. MEC contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant human MEC is a 12.3 kDa protein containing 108 amino acid residues. |
| Protein Sequence | SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY |
| Uniprot ID | Q9NRJ3 |
| Protein RefSeq | NP_683513.1 |
| mRNA RefSeq | NM_148672 |
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