Human Relaxin-2
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| Cat-Nr. | 100-113 |
| Size | 25 µg |
| Price | 199 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 53 |
| Molecular Weight | 6.0 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Data not available. |
| Species Reactivity | Human |
| Synonyms | H2 relaxin, RLN2 |
| Description | Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain. |
| Protein Sequence | A-Chain: QLYSALANKC CHVGCTKRSL ARFC; B-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS |
| Uniprot ID | P04090 |
| Protein RefSeq | NP_005050.2 |
| mRNA RefSeq | NM_005059.3 |
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