Human TECK (CCL25)
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| Cat-Nr. | 100-102 |
| Size | 20 µg |
| Price | 190 € |
| Source | E. coli |
| Formulation | lyophilized |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 127 |
| Molecular Weight | 14.2 kDa |
| Endotoxin Levels | < 0.1 ng/µg of protein (<1EU/µg) |
| Biological Activity | Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells. |
| Species Reactivity | Hamster, Mouse, Human, Monkey, Bacteria |
| Synonyms | CCL25; TECK; Ckb15; SCYA25 |
| Description | TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells. Recombinant human TECK is a 14.2 kDa protein containing 127 amino acid residues, including the four conserved cysteine residues present in CC chemokines. |
| Protein Sequence | QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSRKNVSLL ISANSGL |
| Uniprot ID | O15444 |
| Protein RefSeq | NP_005615.2 |
| mRNA RefSeq | NM_005624 |
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