Human MCP-2 (CCL8) (Animal Free)

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Cat-Nr.100-066S-AF
Size2 µg
Price135 €
SourceE. coli
Formulationlyophilized
Purity Confirmation≥ 98% by SDS-PAGE gel and HPLC analyses.
Length [aa]76
Molecular Weight8.9 kDa
Endotoxin Levels< 0.01 ng/ug of protein (< 0.1 EU/ug)
Biological ActivityDetermined by its ability to chemoattract monocytic leukemia THP-1 cells.
Species ReactivityHamster, Monkey, Mouse, Rat, Human
SynonymsCCL8; HC14; MCP2; MCP-2; SCYA8; SCYA10
DescriptionThe MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 (CCL8) is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Protein SequenceQPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP
Uniprot IDP80075
Protein RefSeqNP_005614
mRNA RefSeqNM_005623

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