Human MCP-2 (CCL8) (Animal Free)
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Cat-Nr. | 100-066S-AF |
Size | 2 µg |
Price | 135 € |
Source | E. coli |
Formulation | lyophilized |
Purity Confirmation | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
Length [aa] | 76 |
Molecular Weight | 8.9 kDa |
Endotoxin Levels | < 0.01 ng/ug of protein (< 0.1 EU/ug) |
Biological Activity | Determined by its ability to chemoattract monocytic leukemia THP-1 cells. |
Species Reactivity | Hamster, Monkey, Mouse, Rat, Human |
Synonyms | CCL8; HC14; MCP2; MCP-2; SCYA8; SCYA10 |
Description | The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 (CCL8) is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. |
Protein Sequence | QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP |
Uniprot ID | P80075 |
Protein RefSeq | NP_005614 |
mRNA RefSeq | NM_005623 |
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