Rabbit Anti-Rat TNF-alpha
Slide this table
Cat-Nr. | 104-P11 |
Size | 100 µg |
Price | 265 € |
Category | Polyclonal Antibody |
Clone Nr. | Rabbit IgG |
Species Reactivity | Rat |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced from sera of rabbits pre-immunized with highly pure recombinant Rat TNF-α. Anti-Rat TNF-α specific antibody was purified by affinity chromatography employing immobilized Rat TNF-α matrix. |
Antigen | recombinant rat TNF-alpha |
Application | ELISA, WB, N, IHC |
Synonyms | Tnf; Tnfa; RATTNF; TNF-alpha |
Description | TNF-α is a pleiotropic pro-inflammatory cytokine secreted by various cells including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands and signals through two receptors, TNFR1 and TNFR2. TNF-α is cytotoxic to a wide variety of tumor cells and is an essential factor in mediating the immune response against bacterial infections. TNF-α also plays a role in the induction of septic shock, auto immune diseases, rheumatoid arthritis, inflammation, and diabetes. Recombinant rat TNF-α is a soluble 157 amino acid protein (17.3 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein. |
Uniprot ID | P16599 |
Protein RefSeq | NP_036807 |
mRNA RefSeq | NM_012675 |
All prices plus VAT + possible delivery charges