Rabbit Anti-Human MIP-3 alpha
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Cat-Nr. | 102-P67 |
Size | 100 µg |
Price | 265 € |
Category | Polyclonal Antibody |
Clone Nr. | Rabbit IgG |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human MIP 3 alpha (human Macrophage Inflammatory Protein-3-alpha). Anti-human MIP 3 alpha specific antibody was purified by affinity chromatography employing immobilized human MIP 3 alpha matrix. |
Antigen | Recombinant human MIP-3 alpha |
Application | ELISA, WB, N |
Synonyms | CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20 |
Description | MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Uniprot ID | P78556 |
Protein RefSeq | NP_004582.1 |
mRNA RefSeq | NM_004591 |
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