Rabbit Anti-Human IL-3
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Cat-Nr. | 102-P33 |
Size | 100 µg |
Price | 265 € |
Category | Polyclonal Antibody |
Clone Nr. | Rabbit IgG |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human IL 3 (human Interleukin-3). Anti-human IL 3 specific antibody was purified by affinity chromatography employing immobilized human IL 3 matrix. |
Antigen | recombinant human IL-3 |
Application | ELISA, WB, N |
Synonyms | IL3; IL-3; MCGF; MULTI-CSF |
Description | IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues. |
Uniprot ID | P08700 |
Protein RefSeq | NP_000579 |
mRNA RefSeq | NM_000588 |
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