Rabbit Anti-Human IGF-1
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| Cat-Nr. | 102-P28 |
| Size | 100 µg |
| Price | 265 € |
| Category | Polyclonal Antibody |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human IGF 1 (Insulin-like Growth Factor-1). Anti-human IGF 1 specific antibody was purified by affinity chromatography employing immobilized human IGF 1 matrix. |
| Antigen | Recombinant human IGF-1 |
| Application | ELISA, WB, IHC, N |
| Synonyms | IGF1; IGFI; IGF-I; IGF1A |
| Description | Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and IGF-II share approximately 70% sequence identity. Both IGF-I and IGF-II are expressed in many tissues and cell types and may have autocrine, paracrine and endocrine functions. Mature IGF-I and IGF-II are highly conserved between the human, bovine and porcine proteins (100% identity), and exhibit cross-species activity. |
| Uniprot ID | P05019 |
| Protein RefSeq | NP_000609.1 |
| mRNA RefSeq | NM_000618.3 |
Reference
- Potentiation of quantal secretion by insulin-like growth factor-1 at developing motoneurons in Xenopus cell culture. Jau-Cheng Liou et al., J Physiol. 2003 Dec 15; 553(Pt 3): 719–728.
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