Hamster Anti-Mouse CD3e
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| Cat-Nr. | 103-M516 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#1T29) |
| Isotype | IgG |
| Antigen | Recombinant mouse CD3e |
| Application | FC, IP |
| Synonyms | T-cell surface antigen T3/Leu-4 epsilon chain |
| Description | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women |
| Uniprot ID | P22646 |
| Protein RefSeq | NP_031674.1 |
| mRNA RefSeq | NM_007648.4 |
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