Rat Anti-Mouse Omgp
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Cat-Nr. | 103-M445 |
Size | 100 µg |
Price | 380 € |
Category | Monoclonal Antibody |
Clone Nr. | (#5H73) |
Isotype | IgG2 |
Species Reactivity | Mouse |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of OMGP. |
Antigen | recombinant mouse Omgp |
Application | WB |
Synonyms | OMG; OMGP |
Description | Oligodendrocyte myelin glycoprotein (OMgp) is a GPI-linked glycoprotein that exhibits multiple leucine-rich repeats and putative N- and O-linked glycosylation sites. It is primarily expressed on the surfaces of oligodendrocytes and large projection neurons, including Purkinje and pyramidal cells. OMgp binds a heterodimeric receptor complex consisting of Nogo R and NGF R/TNFRSF16 to collapse axonal growth cones and inhibit axonal and neurite outgrowth. |
Uniprot ID | Q63912 |
Protein RefSeq | NP_062282.2 |
mRNA RefSeq | NM_019409.2 |
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