Rat Anti-Mouse IL-17 receptor
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Cat-Nr. | 103-M245 |
Size | 100 µg |
Price | 380 € |
Category | Monoclonal Antibody |
Clone Nr. | (#10B27) |
Isotype | IgG2 |
Species Reactivity | Mouse |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-17R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
Antigen | Mouse recombinant EC domain of IL-17R |
Application | WB |
Synonyms | Il17ra; Il17r; Cdw217; VDw217; AW538159 |
Description | IL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R. |
Uniprot ID | Q60943 |
Protein RefSeq | NP_032385.1 |
mRNA RefSeq | NM_008359.2 |
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