Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2)
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| Cat-Nr. | 103-M230 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#7F52) |
| Isotype | IgG2 |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of the common extracellular domain of HAI-2 isoforms. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
| Antigen | recombinant mouse of the common extracellular region of HAI-2 isoforms |
| Application | WB |
| Synonyms | Spint2; HAI-2; C76321; AL024025 |
| Description | HAIs (HGF activator inhibitor type 2) belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various human tissues, such as adult placenta, kidney, pancreas, prostate and small intestine, and fetal kidney and lung. It translates into a 478 amino acid protein. The human HAI-2 gene maps to chromosome 19q13.1 and encodes a 252 amino acid protein, also designated human placental bikunin or kop (Kunitz domain containing protein over-expressed in pancreatic cancer). HAI-1 and HAI-2 are produced in membrane-associated forms, which are secreted as active, proteolytically truncated proteins. |
| Uniprot ID | Q9WU03 |
| Protein RefSeq | NP_035594.1 |
| mRNA RefSeq | NM_011464.2 |
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