Rat Anti-Mouse CD8a
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| Cat-Nr. | 103-M106 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#MAB0708) |
| Isotype | IgG2 |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse Thymus/Spleen Tissues. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | Mouse Thymus and Spleen Tissues |
| Application | IHC, FC |
| Synonyms | Cd8a; Ly-2; Ly-B; Ly-35; Lyt-2; BB154331 |
| Description | CD8 is a heterodimeric glycoprotein consisting of an alpha and beta chain. It is expressed on cytolytic T cells and functions in conjunction with the T cell receptor in the recognition of MHC/peptide complexes. |
| Uniprot ID | P01731 |
| Protein RefSeq | NP_001074579.1 |
| mRNA RefSeq | NM_001081110.2 |
Reference
- Vaccine-induced Aβ-specific CD8+ T cells do not trigger autoimmune neuroinflammation in a murine model of Alzheimer's disease. Rosset M.B. et al., J Neuroinflammation. 2015 May 16;12:95.
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