Rat Anti-Mouse CD4
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| Cat-Nr. | 103-M105 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#MAB0707) |
| Isotype | IgG2 |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse CTL cells. IgG2 fraction of the culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | mouse CTL cells |
| Application | IHC (P), FC |
| Synonyms | Cd4; L3T4; Ly-4 |
| Description | CD4 is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T cells. In humans, CD4 is also expressed to a lesser extent on monocytes and macrophage related cells. |
| Uniprot ID | P06332 |
| Protein RefSeq | NP_038516.1 |
| mRNA RefSeq | NM_013488.2 |
Reference
- A practical approach to pancreatic cancer immunotherapy using resected tumor lysate vaccines processed to express α-gal epitopes. Kenta Furukawa et al., PLoS One. 2017; 12(10): e0184901.
- Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated Fli-1-haploinsufficient mice. Taniguchi T. et al., Arthritis Rheumatol. 2015 Feb;67(2):517-26.
- Regulatory B cells suppress imiquimod-induced, psoriasis-like skin inflammation. Yanaba K. et al., J Leukoc Biol. 2013 Oct;94(4):563-73.
- CD19 Expression in B Cells Regulates Atopic Dermatitis in a Mouse Model. K. Yanaba et al., Am J Pathol. 2013 Jun; 182(6): 2214–2222.
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