Mouse Anti-Human NAP-2 (CXCL7)
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Cat-Nr. | 101-M81 |
Size | 500 µg |
Price | 275 € |
Category | Monoclonal Antibody |
Isotype | IgG1, kappa |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced in BALB/c mice using recombinant human NAP-2 as the immunizing antigen. This IgG1/K antibody was purified from a Protein A chromatography column. |
Antigen | Recombinant Human NAP-2 |
Application | ELISA |
Synonyms | CXCL7, NAP1L4; NAP2; NAP2L; hNAP2; NAP1L4b |
Description | NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP). NAP-2 chemoattracts and activates neutrophils. Recombinant human NAP-2 protein is a 7-8 kDa protein containing 70 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines, and also including the ELR motif common to CXC chemokines that bind to CXCR1 and CXCR2. |
Uniprot ID | P02775 |
Protein RefSeq | NP_002695.1 |
mRNA RefSeq | NM_002704.3 |
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