Mouse Anti-Human MIP-3 alpha
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Cat-Nr. | 101-M79 |
Size | 500 µg |
Price | 275 € |
Category | Monoclonal Antibody |
Isotype | IgG1, kappa |
Species Reactivity | Human |
Formulation | lyophilized from PBS |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
Preparation | Produced from a hybridoma using purified recombinant, E. coli derived, human MIP-3 alpha. This IgG1k antibody was purified on a Protein G affinity column. |
Antigen | Recombinant mouse MIP-3 alpha |
Application | ELISA, WB |
Synonyms | CCL20; CKb4; LARC; ST38; MIP3A; MIP-3a; SCYA20 |
Description | MIP-3α is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. Human MIP-3α is an 8.0 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. |
Uniprot ID | P78556 |
Protein RefSeq | NP_004582.1 |
mRNA RefSeq | NM_004591 |
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