Mouse Anti-Human NT-4

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Cat-Nr.101-M763
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#31A1)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NT-4.
Antigenrecombinant human NT-4
ApplicationWB
SynonymsNTF4; NT4; NT5; NT-4; NT-5; NTF5; GLC10; GLC1O; NT-4/5
DescriptionNT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle. NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons. Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).
Uniprot IDP34130
Protein RefSeqNP_006170.1
mRNA RefSeqNM_006179.4

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