Mouse Anti-Human TNFSF18 (GITR Ligand)
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Cat-Nr. | 101-M677 |
Size | 100 µg |
Price | 380 € |
Category | Monoclonal Antibody |
Clone Nr. | (#4Q25) |
Isotype | IgG1 |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TNFSF18 extracellular domain (also called GITR ligand). |
Antigen | Human recombinant TNFSF18 EC domain |
Application | FC, N, Detection Ab |
Synonyms | TNFSF18; TL6; AITRL; GITRL; hGITRL |
Description | GITR Ligand (GITRL) is a member of the TNF superfamily and has been designated TNFSF18. The carboxy-terminal extracellular domain shows sequence similarily to TNF-alpha/TNFSF1A, Fas Ligand/TNFSF6, TRAIL/TNFSF10, and TNF-beta/TNFSF1B. GITRL is constitutively expressed in human umbilical vein endothelial cells but is not expressed in resting or stimulated T cell lines, B cell lines or peripheral blood mononuclear cells. |
Uniprot ID | Q9UNG2 |
Protein RefSeq | NP_005083.2 |
mRNA RefSeq | NM_005092.3 |
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