Mouse Anti-Human DRAK2
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Cat-Nr. | 101-M593 |
Size | 100 µg |
Price | 380 € |
Category | Monoclonal Antibody |
Clone Nr. | (#4U29) |
Isotype | IgG2 |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
Antigen | Recombinant human DRAK2 |
Application | WB |
Synonyms | Serine/threonine-protein kinase 17B, DAP kinase-related apoptosis-inducing protein kinase 2 |
Description | STK17B (also known as DRAK2) is a member of the serine/threonine kinase family and is related to death-associated protein kinase that triggers apoptosis. STK17B is selectively important for T-cell survival and inhibition of STK17B has therapeutic potential for autoimmune disease. T-cell survival depends on a balance of T-cell receptor and co-stimulatory signals and deficiency of STK17B can affect autoimmune disease susceptibility without generalized suppression of the immune system. |
Uniprot ID | O94768 |
Protein RefSeq | NP_004217.1 |
mRNA RefSeq | NM_004226.3 |
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