Mouse Anti-Human NrCAM
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| Cat-Nr. | 101-M591 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#8E25) |
| Isotype | IgG2 |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NrCAM. |
| Antigen | recombinant human NrCAM |
| Application | WB |
| Synonyms | NRCAM |
| Description | NgCAM related cell adhesion molecule (or NrCAM), also known as Bravo, belongs to the L1 family of cell adhesion molecules, which includes L1, neurofascin and close homolog of L1 (CHL-1/L1CAM-2). These molecules are type I transmembrane proteins that have six Ig-like domains and 4 to 5 Fibronectin type III-like domains in their extracellular region. They also share a conserved cytoplasmic region containing an ankyrin-binding site. L1 family cell adhesion molecules are expressed primarily in the nervous system where they share overlapping functions in controlling axonal growth and guidance. |
| Uniprot ID | Q92823 |
| Protein RefSeq | NP_005001.3 |
| mRNA RefSeq | NM_005010.4 |
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