Mouse Anti-Human IL-22 BP

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Cat-Nr.101-M507
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#6G47)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-22BP.
Antigenrecombinant human IL-22BP
ApplicationWB
SynonymsIL22RA2; CRF2X; CRF2-10; CRF2-S1; IL-22BP; IL-22RA2
DescriptionInterleukin 22 binding protein (IL-22BP), also known as cytokine receptor family (CRF) 2-10, CRF2-X, and IL-22 RA2, is a secreted glycoprotein belonging to the type II cytokine receptor family. IL-22BP antagonizes IL-22 activity by specifically binding IL-22 with high affinity and blocking its interaction with the cell surface IL-22 receptor heteromeric complex composed of IL-22R and IL-10R2 (IL-10 R beta). The highest levels of IL-22BP expression are found in breast, lungs and colon.
Uniprot IDQ969J5
Protein RefSeqNP_443194.1
mRNA RefSeqNM_052962.2

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