Mouse Anti-Human IL-17 receptor

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Cat-Nr.101-M484
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#8D15)
IsotypeIgG2
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-17R extracellular domain.
Antigenrecombinant human IL-17R EC domain
ApplicationWB, N
SynonymsIL17RA; CD217; IL17R; CANDF5; CDw217; IL-17RA; hIL-17R
DescriptionIL-17 binds to IL-17 receptors (IL-17 R), which share no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The amino acid sequence of human IL-17 R is 69% identical to mouse IL-17 R.
Uniprot IDQ96F46
Protein RefSeqNP_055154.3
mRNA RefSeqNM_014339.6

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