Mouse Anti-Human Dihydrofolate Reductase
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| Cat-Nr. | 101-M365 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#24A8) |
| Isotype | IgG2 |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
| Antigen | Recombinant human Dihydrofolate Reductase |
| Application | WB, IHC (P), ICC |
| Synonyms | Dihydrofolate reductase |
| Description | Dihydrofolate reductase (DHFR), also called dihydrofolic acid reductase, are enzymes that hydrogenate folic acid to dihydrofolic acid (DHF) and DHF to tetrahydrofolic acid (THF). These reactions activate the vitamin folic acid and are essential for nucleotide biosynthesis in all living organisms. In humans, DHFR is found in all tissue types. Mutations at the DHFR gene can cause dihydrofolate reductase deficiency, and this megaloblastic anemia. |
| Uniprot ID | P00374 |
| Protein RefSeq | NP_000782.1 |
| mRNA RefSeq | NM_000791.3 |
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