Mouse Anti-Human Clusterin
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Cat-Nr. | 101-M254 |
Size | 100 µg |
Price | 380 € |
Category | Monoclonal Antibody |
Clone Nr. | (#11E38) |
Isotype | IgG1 |
Species Reactivity | Human |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity. |
Antigen | Recombinant Human Clusterin |
Application | E |
Synonyms | Aging-associated gene 4 protein, Apolipoprotein J, Complement cytolysis inhibitor (CLI), Complement-associated protein SP-40, Ku70-binding protein 1 |
Description | Clusterin (apolipoprotein J) is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging |
Uniprot ID | P10909 |
Protein RefSeq | NP_001822.3 |
mRNA RefSeq | NM_001831.3 |
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