Mouse Anti-Human Clusterin

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Cat-Nr.101-M254
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#11E38)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionReconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
AntigenRecombinant Human Clusterin
ApplicationE
SynonymsAging-associated gene 4 protein, Apolipoprotein J, Complement cytolysis inhibitor (CLI), Complement-associated protein SP-40, Ku70-binding protein 1
DescriptionClusterin (apolipoprotein J) is a 75-80 kDa disulfide-linked heterodimeric protein associated with the clearance of cellular debris and apoptosis. In humans, clusterin is encoded by the CLU gene on chromosome 8. CLU is a molecular chaperone responsible for aiding protein folding of secreted proteins, and its three isoforms have been differentially implicated in pro- or antiapoptotic processes. Through this function, CLU is involved in many diseases related to oxidative stress, including neurodegenerative diseases, cancers, inflammatory diseases, and aging
Uniprot IDP10909
Protein RefSeqNP_001822.3
mRNA RefSeqNM_001831.3

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