Mouse Anti-Human VEGF165b

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Cat-Nr.101-M180
Size100 µg
Price380 €
CategoryMonoclonal Antibody
Clone Nr.(#7F17)
IsotypeIgG1
Species ReactivityHuman
Formulationlyophilized
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and StorageLyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with recombinant human VEGF-165b C-terminal peptide. IgG1 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography.
Antigenhuman VEGF-165b c-terminal peptide
ApplicationWB, IHC
Synonymsvascular endothelial growth factor A; VEGFA; VPF; VEGF; MVCD1
DescriptionVEGF165b is an mRNA splice variant of VEGF. Alternative exon usage results in a 165 aa product that is identical to VEGF165 except for 6 unique amino acids at the C-terminus. VEGF165b inhibits proliferation and migration of endothelial cells and is down-regulated in renal cell carcinomas.
Uniprot IDP15692-8
Protein RefSeqNP_001020421
mRNA RefSeqNM_001171629

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