Mouse Anti-Human EDG-1
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| Cat-Nr. | 101-M156 |
| Size | 100 µg |
| Price | 380 € |
| Category | Monoclonal Antibody |
| Clone Nr. | (#21L9) |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with human recombinant Endothelial Differentiation Gene-1 (EDG-1) protein. IgG1 fraction of culture supernatant was purified by Protein G affinity chromatography. |
| Antigen | recombinant human EDG-1 protein |
| Application | WB, IHC (P), FC |
| Synonyms | S1PR1; EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362 |
| Description | S1P1, also known as EDG1, is a member of the endothelial differentiation gene family. It is a high affinity G proteincoupled receptor for the bioactive lipid, Sphingosine1phosphate. S1P1 signaling regulates endothelial cell survival, cytoskeletal remodeling, chemotaxis, and angiogenesis. |
| Uniprot ID | P21453 |
| Protein RefSeq | NP_001391.2 |
| mRNA RefSeq | NM_001400.4 |
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