Mouse Anti-Human IL-6
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| Cat-Nr. | 101-M06 |
| Size | 500 µg |
| Price | 275 € |
| Category | Monoclonal Antibody |
| Isotype | IgG2 |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c mice using highly pure (>98%) recombinant human IL-6 as the immunizing antigen. This IgG1K antibody was purified from cell culture by Protein A affinity chromatography. |
| Antigen | Recombinant Human IL-6 |
| Application | ELISA, WB |
| Synonyms | IL6; HGF; HSF; BSF2; IL-6; IFNB2 |
| Description | IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. |
| Uniprot ID | P05231 |
| Protein RefSeq | NP_000579 |
| mRNA RefSeq | NM_000600 |
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