Mouse Anti-Human Eotaxin-2
Slide this table
| Cat-Nr. | 101-M01 |
| Size | 500 µg |
| Price | 275 € |
| Category | Monoclonal Antibody |
| Isotype | IgG1, kappa |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c mice using highly pure recombinant Human Eotaxin-2 as the immunizing antigen. IgG1/K antibody was purified from ascites fluid by antigen affinity chromatography. |
| Antigen | Recombinant Human Eotaxin-2 (CCL24) |
| Application | ELISA, WB, IHC (P) |
| Synonyms | CCL24; Ckb-6; MPIF2; MPIF-2; SCYA24 |
| Description | Eotaxin2, also named MPIF-2 and Ckβ6, is a CC chemokine that is designated CCL24. Eotaxin2 cDNA encodes a 10.5 kDa, 119 amino acid residue precursor protein with a 26 aa residue signal peptide that is cleaved to generate a mature protein predicted to contain 93 amino acid residues with an N-glycosylation site. C-terminally truncated variants with 78, 73, 75 and 76 residues have also been described. Eotaxin 2 shares 40%, 42% and 39% amino acid sequence identity with other CC chemokines CCL7/MCP3, CCL3/MIP1α, and CCL11/Eotaxin, respectively. Eotaxin2 mRNA is weakly expressed in activated monocytes and T lymphocytes. Recombinant Eotaxin2 induces chemotaxis of eosinophils, basophils, and resting T lymphocytes, but not monocytes or activated T lymphocytes. Eotaxin2 also suppresses colony formation by high proliferative multipotential hematopoietic progenitors. On eosinophils, the effects of Eotaxin2, Eotaxin and CCL13/MCP4 are mediated by the receptor CCR3. |
| Uniprot ID | O00175 |
| Protein RefSeq | NP_002982.2 |
| mRNA RefSeq | NM_002991 |
All prices plus VAT + possible delivery charges