Description / Omgp
Oligodendrocyte myelin glycoprotein (OMgp) is a GPI-linked glycoprotein that exhibits multiple leucine-rich repeats and putative N- and O-linked glycosylation sites. It is primarily expressed on the surfaces of oligodendrocytes and large projection neurons, including Purkinje and pyramidal cells. OMgp binds a heterodimeric receptor complex consisting of Nogo R and NGF R/TNFRSF16 to collapse axonal growth cones and inhibit axonal and neurite outgrowth.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#5H73) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of OMGP. |
| Antigen | recombinant mouse Omgp |
| Application | WB |
| Synonyms | OMG; OMGP |
| Uniprot ID | Q63912 |
| Protein RefSeq | NP_062282.2 |
| mRNA RefSeq | NM_019409.2 |