Description / NrCAM
NgCAM related cell adhesion molecule (or NrCAM), also known as Bravo, belongs to the L1 family of cell adhesion molecules, which includes L1, neurofascin and close homolog of L1 (CHL-1/L1CAM-2). These molecules are type I transmembrane proteins that have six Ig-like domains and 4 to 5 Fibronectin type III-like domains in their extracellular region. They also share a conserved cytoplasmic region containing an ankyrin-binding site. L1 family cell adhesion molecules are expressed primarily in the nervous system where they share overlapping functions in controlling axonal growth and guidance.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#8E25) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with extracellular domain of human recombinant protein of NrCAM. |
| Antigen | recombinant human NrCAM |
| Application | WB |
| Synonyms | NRCAM |
| Uniprot ID | Q92823 |
| Protein RefSeq | NP_005001.3 |
| mRNA RefSeq | NM_005010.4 |