Description / human Neuritin protein
Neuritin is a neurotrophic factor, which is expressed in response to induction of neuronal activity by NGF, BDNF, NT3, and other neural stimulators. It is expressed primarily in postmitotic-differentiating neurons of the developing nervous system and in neuronal structures related to synaptic plasticity in the adult nervous system. Neuritin acts as a molecular mediator of neurite outgrowth, neuronal survival, and synaptic maturation. Recombinant human Neuritin is a covalently disulfide-linked homodimer, consisting of two 9.72 kDa polypeptide monomers, each containing 88 amino acid residues.
More Information
| Size | 5 µg |
|---|---|
| Source | E. coli |
| Biological Activity | Determined by a cell proliferation using rat C6 cells. The ED50 for this effect is 20.0-30.0 ng/ml. |
| Purity Confirmation | > 98% by SDS-PAGE & HPLC analyses |
| Length [aa] | 88 |
| Molecular Weight | 9.72 kDa |
| Species Reactivity | Rat |
| Formulation | lyophilized |
| Protein Sequence | AGKCDAVFKG FSDCLLKLGD SMANYPQGLD DKTNIKTVCT YWEDFHSCTV TALTDCQEGA KDMWDKLRKE SKNLNIQGSL FELCGSGN |
| Synonyms | CPG15, NRN1 |
| Uniprot ID | Q9NPD7 |
| Protein RefSeq | NP_057672.1 |
| mRNA RefSeq | NM_016588.2 |