Description / Neogenin
Neogenin (NEO) is a type I transmembrane protein that is crucial for axonal guidance and neuronal migration, acting as a receptor for Netrins. NEO is also involved in regulating differentiation programs in many embryonic and adult tissues. Mouse NEO is widely expressed in adult tissues and is expressed throughout the mid to late stages of gestation, in both neuronal and non-neuronal tissues. Mouse NEO shares 96%, 93% and 86% amino acid sequence identity with rat, human and chicken NEO, respectively.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#3G55) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with purified mouse recombinant protein of Neogenin. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
| Antigen | mouse recombinant protein of Neogenin |
| Application | WB, IHC (P) |
| Synonyms | Neo1; Igdcc2; AI327052; 2610028H22Rik; D930014N22Rik |
| Uniprot ID | E9QK04 |
| Protein RefSeq | NP_032710.2 |
| mRNA RefSeq | NM_008684.2 |