Description / anti-human MIG monoclonal antibody
MIG, a CXC chemokine, is produced by IFN stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1, kappa |
| Biological Activity | WB: Use at 0.5 - 1.0 µg/ml. |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c mice using highly pure recombinant human MIG as the immunizing antigen. This IgG1K antibody was purified from cell culture by Protein G affinity chromatography. |
| Antigen | Recombinant Human MIG (CXCL9) |
| Application | ELISA, WB |
| Synonyms | CXCL9; CMK; MIG; Humig; SCYB9; crg-10 |
| Uniprot ID | Q07325 |
| Protein RefSeq | NP_002407.1 |
| mRNA RefSeq | NM_002416.1 |