anti-mouse MCP-3 polyclonal antibody Anti-Mouse 100 µg
Description / anti-mouse MCP-3 polyclonal antibody
Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP 3 gene. Mouse MARC/MCP3 expression has also been detected during murine experimental allergic encephalomyelitis in the spinal cord, and in LPS-stimulated murine WEHI 3 cells and Swiss 3T3 cells where MARC expression is glucocorticoidattenuated. Except for one amino acid subsititution, mouse MARC is identical to mouse FIC, the product of a growth factoractivated gene. The mouse MARC cDNA encodes a 97 amino acid residue precursor protein with a 23 amino acid residue signal peptide that is cleaved to yield a 74 amino acid residue mature protein. Mouse CCR2, a mouse chemokine receptor, has been shown to bind JE/MCP1 with high affinity and MARC/MCP3 with lower affinity.
More Information
| Size | 100 µg |
|---|---|
| Source | Goat |
| Clone Nr. | Goat IgG |
| Species Reactivity | Mouse |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine MCP-3 (murine Macrophage/Monocyte chemotactic protein-3). Anti-murine MCP-3 specific antibody was purified by affinity chromatography employing immobilized murine MCP-3 |
| Antigen | Recombinant Mouse MCP-3 |
| Application | ELISA, WB |
| Synonyms | Ccl7; fic; marc; mcp3; MCP-3; Scya7 |
| Uniprot ID | Q03366 |
| Protein RefSeq | NP_038682.1 |
| mRNA RefSeq | NM_013654.3 |