human Maspin (SerpinB5) protein Human 5 µg

In stock

Cat-Nr.
100-347S
Size
5 µg
  €112.00

Description / human Maspin (SerpinB5) protein

Maspin (mammary serine protease inhibitor) is a non-inhibitory serpin that is expressed predominantly in normal mammary epithelial cells but at significantly reduced levels or absent in most breast carcinomas. It has the ability to block the growth, invasiveness, and metastatic potential of breast and lung tumors. This anti-tumor activity is achieved, in part, by the ability of Maspin to inhibit angiogenesis and to preferentially promote apoptosis of tumor cells. Recombinant human Maspin is a 42.2 kDa non-glycosylated protein containing 375 amino acid residues.

More Information

Size 5 µg
Source E. coli
Biological Activity Data not available.
Purity Confirmation > 97% by SDS-PAGE & HPLC analyses
Length [aa] 375
Molecular Weight 42.1 kDa
Species Reactivity Human
Formulation lyophilized
Protein Sequence MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDIPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM EATFCMGNID SINCKIIELP FQNKHLSMFI LL
Synonyms SERPINB5; PI5; maspin
Uniprot ID P36952
Protein RefSeq NP_002630.2
mRNA RefSeq NM_002639

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