Description / Ly-6G (Gr-1)
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Gr-1+ cells have recently been implicated in the development of antitumor responses.
More Information
| Size | 100 µg |
|---|---|
| Source | Rat |
| Isotype | IgG2 |
| Clone Nr. | (#6D17) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with cell lysates of mouse neutrophils. IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography. |
| Antigen | Cell lysates of mouse neutrophils |
| Application | FC, IHC (P) |
| Synonyms | Ly6g; Gr1; Gr-1; Ly-6G |
| Uniprot ID | P35461 |
| Protein RefSeq | CAA50269.1 |
| mRNA RefSeq | XM_001475753.2 |