Description / ILT5
The ILT gene family includes up to 11 members in the human. The extracellular portion of all members includes at least two and usually four immuno-globulin domains. ILT-2 through 5 are all inhibitory members having variable numbers of cytoplasmic ITIM domains. ILT family proteins are expressed predominantly on myeloid lineage cells, and some members have been shown to bind classical (HLA-A and -B) and non-classical (HLA-G1, -E and -F) MHC class I molecules. Several nomenclatures exist, giving each member a different ILT, LIR, LILR, CD85 or other designation.
More Information
| Size | 100 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG2 |
| Clone Nr. | (#9S32) |
| Species Reactivity | Human |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of ILT5 (also called CD85a). |
| Antigen | recombinant human IL T5 |
| Application | WB |
| Synonyms | LILRB3; HL9; ILT5; LIR3; PIRB; CD85A; ILT-5; LIR-3 |
| Uniprot ID | O75022 |
| Protein RefSeq | NP_001074919.1 |
| mRNA RefSeq | NM_001081450.1 |