Description / anti-human IL-4 monoclonal antibody
Interleukin 4 (IL-4) is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. It was initially identified as a B cell differentiation factor (BCDF), as well as a B cell stimulatory factor (BSF1). IL-4 has since been shown to have multiple biological effects on hematopoietic and non-hematopoietic cells, including B and T cells, monocytes, macrophages, mast cells, myeloid and erythroid progenitors, fibroblasts, and endothelial cells. Rat, mouse and human IL-4 are species-specific in their activities.
More Information
| Size | 500 µg |
|---|---|
| Source | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced in BALB/c x C57B1/6 F1 mice using recombinant human IL-4 as the immunizing antigen. IgG2a antibody was purified from ascites fluid on a Protein A affinity column. |
| Antigen | Recombinant human IL-4 |
| Application | ELISA, WB |
| Synonyms | IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1 |
| Uniprot ID | P05112 |
| Protein RefSeq | NP_000580 |
| mRNA RefSeq | NM_000589 |