mouse IL-3 protein Mouse 2 µg

In stock

Cat-Nr.
M10-015S
Size
2 µg
  €85.00

Description / mouse IL-3 protein

IL-3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL-3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL-3 may have additional immunoregulatory roles. Many of the IL-3 activities depend upon co-stimulation with other cytokines. IL-3 is species-specific, variably glycosylated cytokine. Recombinant murine IL-3 is a 15.1 kDa globular protein containing 135 amino acid residues.

More Information

Size 2 µg
Source E. coli
Biological Activity The ED50 as determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is in the range of 20-100 pg/ml.
N Terminal Sequence ASISGR
Purity Confirmation > 98% by SDS-PAGE & Coomassie stain
Length [aa] 140
Molecular Weight 15.8 kDa
Species Reactivity Rat, Mouse, Human, Monkey, Bacteria, Gerbil
Formulation lyophilized
Buffer PBS
Protein Sequence ASISGRDTHR LTRTLNCSSI VKEIIGKLPE PELKTDDEGP SLRNKSFRRV NLSKFVESQG EVDPEDRYVI KSNLQKLNCC LPTSANDSAL PGVFIRDLDD FRKKLRFYMV HLNDLETVLT SRPPQPASGS VSPNRGTVEC
Synonyms Il3; BPA; PSF; HCGF; Il-3; MCGF; Csfmu
Uniprot ID P01586
Protein RefSeq NP_034686.2
mRNA RefSeq NM_010556.4

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