anti-human IL-10 receptor alpha monoclonal antibody Anti-Human 100 µg

In stock

Cat-Nr.
101-M472
Size
100 µg
  €533.00

Description / anti-human IL-10 receptor alpha monoclonal antibody

Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist.

More Information

Size 100 µg
Source Mouse
Isotype IgG2
Clone Nr. (#7Q35)
Species Reactivity Human
Formulation lyophilized
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-10 Ra extracellular domain.
Antigen recombinant human IL-10 Rbalpha EC domain
Application WB
Synonyms IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Uniprot ID Q13651
Protein RefSeq NP_001549.1
mRNA RefSeq NM_001558.3

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