anti-mouse IGF-BP3 monoclonal antibody Anti-Mouse 100 µg

In stock

Cat-Nr.
103-M237
Size
100 µg
  €533.00

Description / anti-mouse IGF-BP3 monoclonal antibody

The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.

More Information

Size 100 µg
Source Rat
Isotype IgG2
Clone Nr. (#11B16)
Species Reactivity Mouse
Formulation lyophilized
Buffer PBS
Reconstitution Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IGF-BP3. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Antigen recombinant mouse protein of IGFBP-3
Application WB
Synonyms Igfbp3; IGFBP-3; IGgfbp3; AI649005
Uniprot ID P47878
Protein RefSeq NP_032369.2
mRNA RefSeq NM_008343.2

All prices plus VAT + possible delivery charges