anti-human IGF-BP3 polyclonal antibody Anti-Human 100 µg
Description / anti-human IGF-BP3 polyclonal antibody
The superfamily of insulin-like growth factor (IGF) binding proteins include the six high-affinity IGF binding proteins (IGFBP) and several low-affinity binding proteins referred to as IGFBP related proteins (IGFBP-rP). All IGFBP superfamily members are cysteine-rich proteins with conserved cysteine residues, which are clustered in the amino- and carboxy-terminal thirds of the molecule. IGFBPs modulate the biological activities of IGF proteins. Some IGFBPs may also have intrinsic bioactivity that is independent of their ability to bind IGF proteins. Post-translational modifications of IGFBP, including glycosylation, phosphorylation and proteolysis, have been shown to modify the affinities of the binding proteins to IGF.
More Information
| Size | 100 µg |
|---|---|
| Source | Rabbit |
| Clone Nr. | Rabbit IgG |
| Species Reactivity | Human |
| Formulation | lyophilized from PBS |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. |
| Stability and Storage | The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C. |
| Preparation | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIGF-BP3 (human IGF-BP3). Anti-hIGF-BP3 specific antibody was purified by affinity chromatography employing immobilized hIGF-BP3 matrix. |
| Antigen | Recombinant human IGF-BP3 |
| Application | ELISA, WB |
| Synonyms | IGFBP3; IBP3; BP-53 |
| Uniprot ID | P17936 |
| Protein RefSeq | NP_001013416 |
| mRNA RefSeq | NM_001013398 |