Description / IFN gamma Receptor-2
The high-affinity IFN-gamma receptor complex is made up of two type I membrane proteins, IFN-gamma R1 and IFN-gamma R2. Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for signaling but does not bind IFN-gamma by itself.
More Information
| Size | 100 µg |
|---|---|
| Source | Armenian Hamster |
| Isotype | IgG |
| Clone Nr. | (#7A25) |
| Species Reactivity | Mouse |
| Formulation | lyophilized |
| Buffer | PBS |
| Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
| Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
| Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a hamster) immunized with purified mouse recombinant protein of INF gamma R2. |
| Antigen | recombinant mouse INF gamma R2 extracellular domain |
| Application | WB, N, IHC |
| Synonyms | Ifngr2; Ifgt; Ifgr2; Interferon gamma receptor 2 |
| Uniprot ID | Q63953 |
| Protein RefSeq | NP_032364.1 |
| mRNA RefSeq | NM_008338.3 |