Description / IFN gamma Receptor-1
The high-affinity IFN-gamma receptor complex is made up of two type I transmembrane proteins, IFN-gamma R1 (IFN-gamma R alpha) and IFN-gamma R2 (IFN-gamma R beta). Both proteins are members of the type II cytokine receptor family. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling, but does not bind IFN-gamma by itself.
More Information
Size | 100 µg |
---|---|
Source | Rat |
Isotype | IgG2 |
Clone Nr. | (#7K23) |
Species Reactivity | Mouse |
Formulation | lyophilized |
Buffer | PBS |
Reconstitution | Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. |
Stability and Storage | Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity. |
Preparation | This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with purified mouse recombinant protein of INF gamma R1. |
Antigen | recombinant mouse proteinof IFN-gamma R1 |
Application | WB, IHC (P) |
Synonyms | Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR; Interferon gamma Receptor 1 |
Uniprot ID | P15261 |
Protein RefSeq | NP_034641.1 |
mRNA RefSeq | NM_010511.2 |